Doctors at Columbia University conducted the pilot trial after identifying the immune cells responsible for destroying hair follicles in people with the condition
WENN
Experiments: Gail Porter is affected by alopecia totalis
A pill that appears to cure alopecia baldness has fully restored the hair of three patients.
Doctors conducted the pilot trial after identifying the immune cells responsible for destroying hair follicles in people with the condition.
Within four or five months of being put on the drug, ruxolitinib, all three patients experienced complete hair growth.
US lead researcher Dr Raphael Clynes, from Columbia University Medical Center in New York, said: 'We've only begun testing the drug in patients, but if the drug continues to be successful and safe, it will have a dramatic positive impact on the lives of people with this disease.'
However, more research is needed before the drug can safely be used as a baldness treatment.
Alopecia is a common autoimmune disease that leads to partial or total hair loss.
PA
Study: Results recorded at Columbia University Medical Center
One of its best known sufferers is former model and TV presenter Gail Porter, who refused to wear a hat or wig to hide her baldness.
There is no connection between alopecia and male pattern baldness that affects 6.5 million men in the UK and is hormone-driven.
The trial followed tests on mice using two new drugs known as JAK inhibitors that can be taken in pill form and block immune pathways.
In mouse experiments, both drugs completely restored the hair of animals with alopecia within 12 weeks.
The trial patients all had moderate-to-severe alopecia areata, which causes patchy loss of head hair.
'We still need to do more testing to establish that ruxolitinib should be used in alopecia areata, but this is exciting news for patients and their physicians,' Dr Clynes said.
Gail Porter is affected by a more serious form of the condition called alopecia totalis, which results in complete baldness.
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